In recent years, with the increasingly severe global aging problem, anti-aging research has become a hot topic in the scientific community. In this field, China's scientific research teams have made remarkable new progress. A randomized, double-blind, placebo-controlled, multicenter clinical study led by the Xiyuan Hospital of the China Academy of Chinese Medical Sciences and conducted in collaboration with 8 research institutions was published in Phytomedicine, a prestigious journal in the international medical field.

The study included 530 participants aged 30 to 78 years. The results showed that elderly participants taking Bazi Bushen capsules showed significant improvement in multiple aging indicators.

Specifically, the Bazi Bushen group showed a 13.79-point reduction in the Kidney-Essence Deficiency Aging Assessment Scale score, which was 2.3 times that of the placebo group. Simultaneously, the Bazi Bushen group also showed a significant decrease in frailty indicators, with a reduction rate 2.3 times that of the placebo group. In addition, Bazi Bushen capsules also significantly improved participants' quality of life and motor function, such as five times sit-to-stand time, grip strength, balance test, walking speed, and muscle mass. Furthermore, Bazi Bushen capsules increased telomerase activity; the study showed that the telomerase activity in the Bazi Bushen capsule group was significantly higher than that in the placebo group, reaching 76.7%.

Anti-aging mechanism of Bazi Bushen capsules

Multiple experimental research results have confirmed the anti-aging effect of Bazi Bushen capsules. A paper published in Biomedicine & Pharmacotherapy showed that Bazi Bushen capsules can improve memory and muscle endurance in naturally aging mice, reverse age-related methylation changes in naturally aging mice, significantly reduce their DNA methylation age, and extend their healthspan.

As a traditional Chinese medicine anti-aging drug, Bazi Bushen capsules have a significant effect in delaying aging. Its unique anti-aging mechanism and extensive systemic intervention effects provide new ideas and approaches for traditional Chinese medicine anti-aging research.

Under the current social context of increasingly severe aging and the early onset and high incidence of age-related diseases, the research and application of Bazi Bushen capsules have important scientific value and social significance. In the future, with the deepening of research and the promotion of application, Bazi Bushen capsules are expected to become one of the important means to promote longevity and quality of life.

References:

[1] Mei J , Ju C , Wang B ,et al.Corrigendum to "The Efficacy and Safety of Bazi Bushen Capsule in Treating Premature Aging: A Randomized, Double Blind, Multicenter, Placebo-controlled Clinical Trial" [Phytomedicine. 2024 Jul 25; 130:155742][J].Phytomedicine, 2024,132(000):2.DOI:10.1016/j.phymed.2024.155869.

[2] Xinjing Mao, Bazi Bushen mitigates epigenetic aging and extends healthspan in naturally aging mice, Biomedicine & Pharmacotherapy,Volume 160,2023,114384,ISSN 0753-3322,DOI: 10.1016/j.biopha.2023.114384.